Clinical Presentation and Complications ofMucormycosis in Patients Presented with Rhinosinusitis

Abstract

Mucormycosis is an emerging life-threatening tropical fungal
infection with potentially devastating consequences, especiallyinpatients with CRS. This cross-sectional study wants to establishtheincidence of mucormycosis, the clinical manifestations, andtheimplications among patients with CRS within a local tertiaryhealthcare institution. In this cross-sectional descriptive study, confirmed cases of mucormycosis were 171. Studies showedthatfacial pain, nasal obstruction, and proptosis as common symptoms, and patients with diabetes mellitus are at high risk. Radiological
investigations often revealed mucosal thickening of the noseandsinuses; serological examinations revealed a suboptimal glycaemicprofile. The study also pointed out serious consequences suchasblindness and intracranial spread therefore requiringearlydiagnosis and intensive management. This study underscorestheneed to identify mucormycosis in vulnerable patient groups andcalls for better clinical vigilance and treatment strategies topreventthe devastating effects of the infection. Keywords: Mucormycosis, Chronic Rhinosinusitis, Facial Pain, Diabetes Mellitus, Complications, Imaging Studies, EarlyDiagnosis